簡(jian)要描述(shu):英文名稱: BIO (2’Z,3’E)-6-Bromoindirubin-3-oxime產品應用: WNT信號通路抑制劑中國俗稱: GSK3激酶抑制劑 注冊品牌: StemRD 生產廠家: 美國StemRD公司訂購貨號: BIO-005規格型號: 5mg保存溫度: ﹣20℃產品種類: 小分子工具到貨時間: 1~5天(tian)
產品目錄
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產品英文名稱: BIO (2’Z,3’E)-6-Bromoindirubin-3-oxime
產品中文名稱: BIO (2’Z,3’E)-6-Bromoindirubin-3-oxime
訂購:
BIO 產品英文簡述:
BIO (6-bromoindirubin-3'-oxime) is a specific GSK3 kinase inhibitor. Inhibition of GSK3-beta results in activation of the canonical WNT pathway leading to the translocation of beta-catenin to the nucleus.
This chemical compound from StemRD is 98.5% pure (HPLC). In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.
Purity: Greater than 98.5% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolr.
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